Epidemiological studies have clearly shown that individuals that regularly eat foods rich in omega-3s are, overall, in better health than those who don’t. However, the results of randomized clinical trials observing the health effects of omega-3 supplementation are mostly positive, but not always conclusive.
One of the hypotheses for the apparent discrepancy in the results between observational population studies and randomized clinical trials is that not all individuals respond the same way to supplementation and that some people may need higher doses than what is typically recommended to obtain the same beneficial health effect.
A good way to ensure that your patients receive the right amount of omega-3s is to measure omega-3 levels in the blood. Ideally, they would be tested before implementing supplementation, at one and three months after the initiation of supplementation, and subsequently on a regular basis to make sure their levels remain consistently high.
Several omega-3 testing methods are available but not all of these methods are comparable. Also note that one laboratory may employ several methods, depending on which one is requested. It is therefore important to make sure that the same laboratory and method are used consistently in order to accurately interpret your patients’ progress.
In 2004, the Omega-3 Index was developed. This index is a measure of omega-3s in the blood, expressed as a percentage of EPA/DHA in relation to the total fatty acid content of the membrane of red blood cells. The Omega-3 Index is emerging as one of the most popular ways to measure and monitor omega-3s in patients. It’s a test that can be done at home and only requires a drop of blood. Patients do not need a prescription to get the test which can be ordered only through a laboratory website.
This index is also used in clinical studies to make sure volunteers are monitored properly and results of the health benefits of omega-3 supplementation can be correlated with the index.
Some clinical studies using sources of omega-3s such as krill oil have already demonstrated that krill oil supplementation is able to increase the omega-3 index.* More research is necessary to confirm that long-term supplementation with omega-3s and increased omega-3 index can lead to improved health over time, especially in already healthy individuals.*
For more information about the omega-3 index and how it helps us understand the correlation between krill oil supplementation and health status, you can visit the website of our krill oil provider Aker BioMarine.